1 result for "ASC" in Products

ASC Products

ASC contains an N-terminal Pyrin domain and C-terminal CARD (Caspase-recruitment Domain), and is a p53 target protein that serves as an adaptor to the pro-apoptotic Bax molecule. The interaction of ASC with Bax promotes apoptosis in response to many apoptotic stimuli. Methylation of the ASC gene has been correlated with decreased protein expression...

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Reactivity: Human
Details: Goat IgG Polyclonal
Applications: KO, WB
Novus Antibodies
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