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Apoptosis signal-regulating kinase 1 (ASK1), also known as MEKK5 and MAP3K5, is a cytoplasmic protein that is induced by inflammatory cytokines, UV light, and other stress-related stimuli. ASK1 phosphorylates MAP kinase kinases that in turn activate the p38 and JNK families of MAP kinases. Mice lacking ASK1 are resistant to stress-induced p38 and J...

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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #2E4
Applications: IHC, WB, ELISA, Flow, ICC/IF
Western Blot: ASK1 Antibody (2E4)BSA Free [NBP2-37592]
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