1 result for "BACE-1" in Products

BACE-1 Products

Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding si...

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Reactivity: Human, Mouse
Details: Mouse IgG1 Monoclonal Clone #137626
Applications: B/N, IP
Novus Antibodies
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