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209 results for "BACE-1" in Products
BACE-1 Products
Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137612 |
| Applications: | IHC, WB, Flow, CyTOF-ready |
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| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | P56817.1 |
| Applications: | Enzyme Activity |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137626 |
| Applications: | B/N, IP |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #3C1C3 |
| Applications: | WB, ELISA, Flow, ICC/IF, CyTOF-ready |
![Western Blot: BACE-1 Antibody (3C1C3)BSA Free [NBP2-37261]](https://resources.rndsystems.com/images/products/BACE-1-Antibody-3C1C3-Western-Blot-NBP2-37261-img0004.jpg "Western Blot: BACE-1 Antibody (3C1C3)BSA Free [NBP2-37261]")
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: BACE-1 Antibody [NBP1-62416]](https://resources.rndsystems.com/images/products/BACE-1-Antibody-Western-Blot-NBP1-62416-img0017.jpg "Western Blot: BACE-1 Antibody [NBP1-62416]")
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| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
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| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2C1 |
| Applications: | IHC, WB, ELISA, Func |
![Western Blot: BACE-1 Antibody (2C1) [H00023621-M01]](https://resources.rndsystems.com/images/products/BACE-1-Antibody-2C1-Western-Blot-H00023621-M01-img0005.jpg "Western Blot: BACE-1 Antibody (2C1) [H00023621-M01]")
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| Reactivity: | Mouse |
| Source: | NS0 |
| Accession #: | P56818 |
| Applications: | Enzyme Activity |
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| Reactivity: | Human |
| Assay Range: | 0.625-40 ng/mL |
| Applications: | ELISA |
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
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| Reactivity: | Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: BACE-1 Antibody [NBP3-13390]](https://resources.rndsystems.com/images/products/BACE-1-Antibody-Western-Blot-NBP3-13390-img0001.jpg "Western Blot: BACE-1 Antibody [NBP3-13390]")
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Potent and selective β-secretase (BACE) inhibitor
| Chemical Name: | N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide hydrochloride |
| Purity: | ≥98% |
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BACE1 and BACE2 inhibitor
| Chemical Name: | N-[3-[(5R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide |
| Purity: | ≥98% |
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| Reactivity: | Human |
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| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #7C5T7 |
| Applications: | WB |
![Western Blot: BACE-1 Antibody (7C5T7) [NBP3-15398]](https://resources.rndsystems.com/images/products/BACE-1-Antibody-7C5T7-Western-Blot-NBP3-15398-img0001.jpg "Western Blot: BACE-1 Antibody (7C5T7) [NBP3-15398]")
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Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #027 |
| Applications: | Flow, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: BACE-1 Antibody (027) [NBP2-89254]](https://resources.rndsystems.com/images/products/BACE-1-Antibody-027-Immunocytochemistry-Immunofluorescence-NBP2-89254-img0001.jpg "Immunocytochemistry/ Immunofluorescence: BACE-1 Antibody (027) [NBP2-89254]")
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Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE30-40 |
| Applications: | WB |
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| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
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| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
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| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
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| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
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| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
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| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
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| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
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