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Caspase-3 Products

Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin. Normally, it is an inactive, exclusively cytosolic homodimer....

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Reactivity: Human, Mouse, Rat, Gerbil
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, Flow, ICC/IF, IP
Immunohistochemistry: Caspase-3 Antibody - (active/cleaved) [NB100-56113]
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