1 result for "Caspase-3" in Products

Caspase-3 Products

Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin. Normally, it is an inactive, exclusively cytosolic homodimer....

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Reactivity: Human, Mouse, Rat, Porcine, Chicken, +2 More
Details: Mouse IgG1 kappa Monoclonal Clone #31A1067
Applications: KO, IHC, WB, Flow, ICC/IF, + 5 More
Western Blot Detection of Pro and Active Caspase-3 in Whole Cell Protein From Treated Jurkat Cells
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