ECM1 Proteins and Enzymes

Extracellular matrix protein 1 (ECM1) is an 85 kDa, secreted glycoprotein important in connective tissue organization. ECM1 is over-expressed in many malignant epithelial tumors and has demonstrated angiogenic activity. Two disorders associated with diminished function of ECM1, lipoid proteinosis and lichen sclerosis, support a role for ECM1 as a b...