Stabilin-2 Proteins and Enzymes

Stabilin-1 and -2 are type I transmembrane members of a family of fasciclin-like Hyaluronan (HA) receptor homologs. Both contain fasciclin-like adhesion domains, EGF-like repeats, and hyaluronan-binding motifs, and both are expressed on sinusoidal endothelium and macrophages. Functionally, they are distinct. Stabilin-1 acts to clear unwanted self...