TMEM166 Proteins and Enzymes

FUNCTION: Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein. TISSUE SPECIFICITY: Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.