Support for iCE3 to Maurice Transition
Service support for iCE3 is ending in June 2029
Transition to the Maurice Platform- Same technology, same results, more benefits.
Unlock New Features with a Trade-In
Get charge heterogeneity data you trust with the Maurice™ platform, powered by iCE™ technology.
With Maurice, expand your capabilities with CE-SDS options for protein size analysis.
With the MauriceFlex system, get icIEF, CE-SDS, and icIEF Fractionation capabilities.
Control Maurice and MauriceFlex Systems with Waters™ Empower® CDS software, or Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) software
Compare data between iCE3 and Maurice
Publication spotlight
A peer-reviewed global study across 21 different sites demonstrates comparable data between iCE3 and Maurice for a mAb and fusion protein.
Application note
Analysis of three different types of molecules (EPO, mAb, and anti-α1-anti-trypsin) using iCE3 and Maurice results in comparable data.
Method Transfer
This brochure provides an overview of different bridging studies that have been done across laboratories globally.
Bridging Study Insights
Many of your peers have conducted extensive bridging studies while transitioning from iCE to Maurice. Contact us for those invaluable insights.
Maurice Tutorials
Visit the Bio-Techne Academy for an entire library of Maurice videos, including how-tos, working principles, software tutorials and more.
Technical Tips
Optimizing your iCE3 transition experience
In her training series “Technical Tips from Monica Tyagi,” Dr. Tyagi discusses some simple but important steps to facilitate your transition from the iCE3 instrument to the Maurice platforms. She shares data comparability results from key publications, bridging study summaries and models, example timelines, hands on differences between iCE3 and Maurice systems, frequently asked questions (FAQs), and more.
Hear from Your Peers
Approaching Instrument Changes in QC: One Team's Journey Transitioning from the iCE3 to the Maurice C. System
“We assessed relevant instrument and method performance aspects such as sensitivity, proportionality between product concentration and observed signal, baseline comparability, peak position shifts, resolution, relative peak area, and measurement variance. Based on the generated data, we concluded that Maurice C was suitable to seamlessly continue iCE3-based release icIEF measurements.”
Anne Ries, PhD
Scientist, Boehringer Ingelheim
iCE3 Virtual User Meeting 2026 – Transitioning to Maurice
Listen to Leonard Bell from Labcorp, who shared his team’s real-world experience transferring iCE3 methods to Maurice systems. Learn about key challenges, practical solutions, and how this transition opens doors to a more streamlined Analytical Method Lifecycle approach. Following Leonard’s talk, Monica Tyagi from Bio-Techne offered valuable technical tips and highlighted how Maurice platforms can boost your lab’s capabilities and productivity. They are joined during the Q&A with industry experts Seth Madren (Biogen) and Chris Cammarata (J&J).
Compare Workflows
Compare Models
| ICE3 | Maurice | MauriceFlex | Maurice C. | |
| icIEF Charge Application | ✓ | ✓ | ✓ | ✓ |
| CE-SDS Size Application | ✓ | ✓ | - | |
| icIEF Fractionation | - | ✓ | - | |
| Onboard Mixing for Sample Prep | ✓ (Only with the Alcott autosampler) | ✓ | ✓ | |
| Absorbance Detection | ✓ | ✓ | ✓ | ✓ |
| Native Fluorescence Detection (4X Sensitivity) | ✓ | ✓ | ✓ | |
| Integrated Autosampler | ✓ | |||
| Software | Compass for iCE | Compass for iCE, Empower CDS, Chromeleon CDS | Compass for iCE, Empower CDS | Compass for iCE, Empower CDS, Chromeleon CDS |
User Guide
Method Guide
Datasheet
Datasheet
| Catalog Number | Description |
|---|---|
| 101701 | This cartridge has a 50 mm, 100 µm (I.D.) fluorocarbon-coated capillary and built-in electrolyte tanks. |
| 042-848 | The iCE Method Development Kit provides reagents and consumables for method development on the iCE3. It includes sample preparation reagents along with a range of ampholytes, pI markers, and additives for working with different proteins. The kit also contains a test mix to verify iCE3 system readiness and a Method Development Guide for reference during setup and optimization. NOTE: Consumables such as the cartridge and sample vials are not included in the kit. |
| 045-207 | FC and HT Cartridge Wash Kit |
A wide range of markers for pI determination are available to give both consistent and accurate measurement of isoelectric point on your iCE system. They can be used for whole-column and single-point capillary isoelectric focusing (cIEF) detection to measure your sample protein's isoelectric point, and for quality control of sample analysis. You'll get 200 µL of pI marker stock solution in every vial.
| Catalog Number | pI |
|---|---|
| 102018 | pI Marker 3.21 |
| 102350 | pI Marker 4.22 |
| 102224 | pI Marker 5.12 |
| 102220 | pI Marker 6.14 |
| 102226 | pI Marker 7.05 |
| 102407 | pI Marker 7.65 |
| 102408 | pI Marker 8.18 |
| 102349 | pI Marker 9.46 |
| 102232 | pI Marker 10.10 |
| Catalog Number | Description |
|---|---|
| 045-098 | iCE3 Syringe Purge Assembly |
| 102031 | iCE3/iCE280 Snap burst cap, 11 mm |
| 045-132 | Glass Vial, 2 mL, 100/pkg. For iCE280/iCE3 |
| 045-135 | 300 µL Vial Insert. For iCE280 and iCE3 |
| 045-134 | Cap with Septa. For iCE280 and iCE3 |
| 045-133 | Polypropylene Vial. For iCE280 and iCE3 |
| 045-070 | iCE3 Port 2 Cartridge Inlet Sleeve |
| 045-074 | iCE3 MicroInjector transfer capillary |
| 045-139 | iCE3 Amber Vial |
| 102555 | Constant Level Waste Vial |
| 045-089 | iCE3 Waste Line |
| 102677 | iCE3 Port 3 Plug |
| 102531 | Waste Vial Cap |
| 102076 | Polypropylene Vial Insert |
| 102142 | Balancing Waste Vial, 4 mL |
| 102004 | Polypropylene Vial Snap Ring |
| 102032 | Snap Burst Cap, 13 mm |
| 102762 | Polypropylene Vial with Snap Cap and Septum |
| A-0000226-00 | Electrode Holder for iCE3 |
| 101868 | Glass Vial, 2 mL |
| 045-076 | iCE3 Balancing Line |
| 045-140 | iCE3 Waste Bottle w/ Check Valve |
| Catalog Number | Description |
|---|---|
| 045-048 | iCE3 96+4 Sample Tray for Alcott 720 Autosampler |
| 045-138 | DI Water Supply Bottle, Alcott 720NV |
| 045-072 | iCE3 Transfer Line, Alcott 720NV |
| 102765 | Polypropylene Vial with Snap Cap and Septum for Alcott Autosamplers |
| 045-079 | Alcott 720 Accessory Kit |
| P-0000025-00 | PrinCE 300 µL Vial |