2-Hydroxypropyl-β-cyclodextrin

Name: 2-Hydroxypropyl- β -cyclodextrin
Brand: Tocris Bioscience
SKU: 0708
Price: 88 USD
Availability: InStock

Tocris Bioscience | Catalog # 0708

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Citations (8)

Product Documents

Solubilization agent

Product Description
Product Specifications
Solubility
Preparing Stock Solutions
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Solubilization agent

Alternative Names

HBC,Hydroxypropyl-β-cyclodextrin

View all Buffers, Chelators and Reagents »

Product Description

The most widely used modified cyclodextrin, the lipophilic cavity formed by 7 glucose units. Drug solubility in water is greatly enhanced by complexing with HBC.

Product Specifications for 2-Hydroxypropyl-β-cyclodextrin

Molecular Weight

1400.00

Formula

(C₆H₉O₅)₇(C₃H₇O)n

Storage

Store at RT

CAS Number

128446-35-5

PubChem ID

44134771

InChI Key

BZRWCHBEBFPRGF-UHFFFAOYSA-N

SMILES

O[C@@H]1[C@H]8C(COCC(C)O)O[C@H](O[C@H](C(COCC(C)O)O[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O[C@H](C(COCC(C)O)O[C@H](O[C@@H]5C(O)C(O)[C@H](O[C@@H]6C(O)C(O)[C@H](O[C@H](C(COCC(C)O)O[C@H](O8)[C@H]7O)[C@H]7O)O[C@@H]6COCC(C)O)O[C@@H]5COCC(C)O)[C@H]4O)[C@@H]4O)OC3COCC(C)O)[C@H]2O)[C@H]2O)[C@H]1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	140	100

Preparing Stock Solutions for 2-Hydroxypropyl-β-cyclodextrin

The following data is based on the product molecular weight 1400.00.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	0.71 mL	3.57 mL	7.14 mL
5 mM	0.14 mL	0.71 mL	1.43 mL
10 mM	0.07 mL	0.36 mL	0.71 mL
50 mM	0.01 mL	0.07 mL	0.14 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

音量

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

Pitha Hydroxypropyl-β-cyclodextrin: preparation and characterisation; effects on solubility of drugs. Int.J.Pharmacol.
Frijlink The effects of cyclodextrins on the disposition of intravenously injected drugs in the rat. Pharm.Res. 1991 PMID: 2052529

Product Documents for 2-Hydroxypropyl-β-cyclodextrin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for 2-Hydroxypropyl-β-cyclodextrin

For research use only

Citations for 2-Hydroxypropyl-β-cyclodextrin

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