Ac4GlcNAlk

Tocris Bioscience | Catalog # 7750

Metabolic chemical reporter for studying glycosylation and glycoproteins
Tocris Bioscience
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Key Product Details

Description

Metabolic chemical reporter for studying glycosylation and glycoproteins

Product Description

Ac4GlcNAlk is a metabolic chemical reporter (MCR) for studying cell surface glycosylation. It is used for identification of O-GlcNAc modified proteins. In cells expressing the engineered pyrophosphorylase, mut-AGX1, Ac4GlcNAlk is efficiently converted into UDP-GlcNAlk which is incorporated into GlcNAlk-containing glycoproteins.

Product Specifications for Ac4GlcNAlk

Molecular Weight

427.41

Formula

C19H25NO10

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

2-Deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-D-glucopyranose-1,3,4,6-tetraacetate

CAS Number

1361993-37-4

PubChem ID

101797984

InChI Key

PODQGPKRSTUNAT-ULAPBGCESA-N

SMILES

CC(OC[C@H]1OC([C@@H]([C@H]([C@@H]1OC(C)=O)OC(C)=O)NC(CCC#C)=O)OC(C)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 42.74 100

Preparing Stock Solutions for Ac4GlcNAlk

The following data is based on the product molecular weight 427.41.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.34 mL 11.70 mL 23.40 mL
5 mM 0.47 mL 2.34 mL 4.68 mL
10 mM 0.23 mL 1.17 mL 2.34 mL
50 mM 0.05 mL 0.23 mL 0.47 mL

Calculators

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product.

Product Documents for Ac4GlcNAlk

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ac4GlcNAlk

For research use only

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