Acarbose

Tocris Bioscience | Catalog # 2673

Glucosidase α inhibitor (intestinal)
Tocris Bioscience

Key Product Details

Description

Glucosidase α inhibitor (intestinal)

Alternative Names

Bay-g 5421
View all Glycosylase Inhibitors »

Product Description

Acarbose is an inhibitor of intestinal α-glucosidase (IC50 = 11 nM). Antidiabetic; inhibits the hydrolysis of complex carbohydrates.

Product Specifications for Acarbose

Molecular Weight

645.25

Formula

C25H43NO18

Storage

Desiccate at RT

Chemical Name

O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-Glucose

CAS Number

56180-94-0

PubChem ID

444254

InChI Key

XUFXOAAUWZOOIT-SXARVLRPSA-N

SMILES

C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 64.52 100
DMSO 64.52 100

Preparing Stock Solutions for Acarbose

The following data is based on the product molecular weight 645.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.55 mL 7.75 mL 15.50 mL
5 mM 0.31 mL 1.55 mL 3.10 mL
10 mM 0.15 mL 0.77 mL 1.55 mL
50 mM 0.03 mL 0.15 mL 0.31 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

Product Documents for Acarbose

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Acarbose

For research use only

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