Acetyl Pepstatin

Name: Acetyl Pepstatin
Brand: Tocris Bioscience
SKU: 5852

Tocris Bioscience | Catalog # 5852

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Product Documents

High affinity HIV-1 and HIV-2 protease inhibitor

Discontinued Product

5852 has been discontinued. View all Additional Synthetic Protease Inhibitors products.

Technical Data
Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

High affinity HIV-1 and HIV-2 protease inhibitor

View all Additional Synthetic Protease Inhibitors »

Product Description

Acetyl Pepstatin is a high affinity aspartic protease inhibitor. Inhibits HIV-1 protease (K_i = 20 nM at pH 4.7) and HIV-2 protease (K_i = 5 nM at pH 4.7). Antiviral.

Product Specifications for Acetyl Pepstatin

Molecular Weight

643.81

Formula

C₃₁H₅₇N₅O₉

Storage

Store at -20°C

CAS Number

11076-29-2

PubChem ID

5481345

InChI Key

WKYBEGDEGRCZNF-LBTYKNIQSA-N

SMILES

O=C(N[C@@H](CC(C)C)[C@@H](O)CC(N[C@@H](C)C(N[C@H]([C@@H](O)CC(O)=O)CC(C)C)=O)=O)[C@H]([C@@H](C)C)NC([C@@H](NC(C)=O)C(C)C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 2mg/ml in PBS

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

音量

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g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Concentration 1 (C1)

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Concentration 2 (C2)

Volume 2 (V2)

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product.

Richards Effective blocking of HIV-1 proteinase activity by characteristic inhibitors of aspartic proteinases. FEBS Lett. 1989 PMID: 2651157
Richards Inhibition of the aspartic proteinase from HIV-2. FEBS Lett. 1989 PMID: 2668032
Matúz Inhibition of XMRV and HIV-1 proteases by pepstatin A and acetyl-pepstatin. FEBS J. 2012 PMID: 22804908

Product Documents for Acetyl Pepstatin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Acetyl Pepstatin

For research use only

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