ACPT-II

Key Product Details

Product Description

ACPT-II is a competitive metabotropic receptor antagonist (K_B values are 115, 88 and 77 μM at mGlu_1a, mGlu₂ and mGlu_4a respectively).

Licensing Information

Sold with the permission of the CNRS

Product Specifications for ACPT-II

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for ACPT-II

The following data is based on the product molecular weight 217.18.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.60 mL	23.02 mL	46.04 mL
5 mM	0.92 mL	4.60 mL	9.21 mL
10 mM	0.46 mL	2.30 mL	4.60 mL
50 mM	0.09 mL	0.46 mL	0.92 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 13 publications citing the usage of this product.

• Bessis Closure of the venus flytrap model of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists. Proc.Natl.Acad.Sci.U.S.A. 2002 PMID: 12151600
• Acher Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor subtypes. J.Med.Chem. 1997 PMID: 9301676

Product Documents for ACPT-II