[Ala1,3,11,15]-Endothelin
Discontinued Product
1197 has been discontinued.
View all Endothelin ETB Receptor Agonists products.
Description: Selective ETB agonist
Biological Activity
[Ala1,3,11,15]-Endothelin is a selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).Technical Data
M.Wt:
2368
Formula:
C109H163N25O32S
Sequence:
ASASSLMDKEAVYFAHLDIIW
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
121204-87-3
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1,3,11,15]ET1.
Nakamichi et al.
Biochem.Biophys.Res.Commun., 1992;182:144 -
Endothelin and structurally related analogs distinguish between endothelin receptor subtypes.
Panek et al.
Biochem.Biophys.Res.Commun., 1992;183:566
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