AMT hydrochloride

Key Product Details

Product Description

AMT hydrochloride is a potent, selective and reversible inhibitor of iNOS (IC₅₀ = 3.6 nM; approximately 30 and 40 times selective over nNOS and eNOS respectively).

Product Specifications for AMT hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for AMT hydrochloride

The following data is based on the product molecular weight 166.67.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	60.00 mL	299.99 mL	599.99 mL
0.5 mM	12.00 mL	60.00 mL	120.00 mL
1 mM	6.00 mL	30.00 mL	60.00 mL
5 mM	1.20 mL	6.00 mL	12.00 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Nakane Novel potent and selective inhibitors of inducible nitric oxide synthase. Mol.Pharmacol. 1995 PMID: 7536889
• Yu Inhibition of sarcoplasmic reticular function by chronic interleukin-6 exposure via iNOS in adult ventricular myocytes. J.Physiol. 2005 PMID: 15845578
• Liao Nitric oxide signaling in stretch-induced apoptosis of neonatal rat cardiomyocytes. FASEB J. 2006 PMID: 16877524

Product Documents for AMT hydrochloride