ARL 67156 trisodium salt

Tocris Bioscience | Catalog # 1283

NTPDase inhibitor
Tocris Bioscience

Key Product Details

Description

NTPDase inhibitor

Alternative Names

FPL 67156
View all NTPDase Inhibitors »

Product Description

ARL 67156 trisodium salt is a selective NTPDase inhibitor (pIC50 = 4.62 and 5.1 in human blood and rat vas deferens respectively). ARL 67156 prevents vascular calcification and extends longevity in Hutchinson-Gilford progeria syndrome mice. ARL 67156 increases neurogenic contract response to nerve stimulation. ARL 67156 enhances parasympathetic neurotransmission in guinea-pig urinary bladder.

Product Specifications for ARL 67156 trisodium salt

Molecular Weight

785.06

Formula

C15H21Br2N5O12P3.3Na

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

6-N,N-Diethyl-D-β,γ-dibromomethyleneATP trisodium salt

CAS Number

1021868-83-6

PubChem ID

52948496

InChI Key

KJYSFRKUFDOOSQ-ZANJJFDZSA-K

SMILES

O[C@H]3[C@H](O)[C@@H](O[C@@H]3COP(OP(C(Br)(Br)P(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)N1C=NC2=C1N=CN=C2N(CC)CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 15.78 20

Preparing Stock Solutions for ARL 67156 trisodium salt

The following data is based on the product molecular weight 785.06.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 6.37 mL 31.84 mL 63.69 mL
1 mM 1.27 mL 6.37 mL 12.74 mL
2 mM 0.64 mL 3.18 mL 6.37 mL
10 mM 0.13 mL 0.64 mL 1.27 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 62 publications citing the usage of this product.

Product Documents for ARL 67156 trisodium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ARL 67156 trisodium salt

For research use only

Citations for ARL 67156 trisodium salt

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  • Prevents degradation of ATP released from cultured cells
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Primary Astrocytes
    Verified Customer | Posted 01/10/2018
    Working concentration of 100 uM
    Used in ATP release assay from cultured cells to inhibit ectonucleotidase function

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