Artesunate

Key Product Details

Product Description

Artesunate suppresses ROS-induced activation of the NLRP3 inflammasome. Arrests cell cycle in the G₂/M phase and sensitizes human renal cell carcinoma (RCC) cell lines to sorafenib in vitro. Aretesumate is an antimalarial (Plasmodium).

Product Specifications for Artesunate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Artesunate

The following data is based on the product molecular weight 384.42.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.60 mL	13.01 mL	26.01 mL
5 mM	0.52 mL	2.60 mL	5.20 mL
10 mM	0.26 mL	1.30 mL	2.60 mL
50 mM	0.05 mL	0.26 mL	0.52 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 7 publications citing the usage of this product.

• Liu Artesunate inhibits renal ischemia-reperfusion-mediated remote lung inflammation through attenuating ROS-induced activation of NLRP3 inflammasome. Inflammation 2018 PMID: 29730819
• Jeong Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis. Oncotarget. 2015 PMID: 26426994
• Meshnick Artemisinin: mechanisms of action, resistance and toxicity. In.J.Parasitol. 2002 PMID: 12435450

Product Documents for Artesunate