AS 19

Tocris Bioscience | Catalog # 1968

Potent 5-HT7 agonist
Tocris Bioscience

Key Product Details

Description

Potent 5-HT7 agonist
View all 5-HT7 Receptor Agonists »

Product Description

AS 19 is a potent 5-HT7 receptor agonist (IC50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia in vivo. AS 19 also promotes melanin synthesis in B16F10 murine melanoma cells.

Product Specifications for AS 19

Molecular Weight

283.41

Formula

C18H25N3

Storage

Desiccate at -20°C

Purity

≥98% (HPLC)

Chemical Name

(2S)-5-(1,3,5-Trimethylpyrazol-4-yl)-2-(dimethylamino)tetralin

CAS Number

1000578-26-6

PubChem ID

23642275

InChI Key

BTTOYOKCLDAHHO-HNNXBMFYSA-N

SMILES

CC1=C(C2=CC=CC3=C2CC[C@H](N(C)C)C3)C(C)=NN1C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 28.34 100
Ethanol 28.34 100

Preparing Stock Solutions for AS 19

The following data is based on the product molecular weight 283.41.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.53 mL 17.64 mL 35.28 mL
5 mM 0.71 mL 3.53 mL 7.06 mL
10 mM 0.35 mL 1.76 mL 3.53 mL
50 mM 0.07 mL 0.35 mL 0.71 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 35 publications citing the usage of this product.

Product Documents for AS 19

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for AS 19

For research use only

Customer Reviews for AS 19 (1)

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  • 5-HT has a potential for relaxant
    Name: Anonymous
    Species: Rat
    Assay Type: In Vivo
    Verified Customer | Posted 02/18/2020
    AS19 (5-HT7) and concentration(0.0001 mol/L)
    AS 19 1968

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