Auxin

Key Product Details

Product Description

Auxin is a chemical dimerizer used in auxin-inducible degron (AID) systems. Induces degradation of a target protein tagged with the auxin-receptor F-box protein Tir1 E3 ligase AID in human colorectral cancer and mouse ES cells or tagged with AFB2 in A431 cells. Endogenous plant hormone.

Product Specifications for Auxin

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Auxin

The following data is based on the product molecular weight 175.18.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.71 mL	28.54 mL	57.08 mL
5 mM	1.14 mL	5.71 mL	11.42 mL
10 mM	0.57 mL	2.85 mL	5.71 mL
50 mM	0.11 mL	0.57 mL	1.14 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Natsume Rapid protein depletion in human cells by auxin-inducible degron tagging with short homology donors. Cell Rep. 2016 PMID: 27052166
• Li An efficient auxin-inducible degron system with low basal degradation in human cells. Nat.Methods. 2019 PMID: 31451765
• Nishimura An auxin-based degron system for the rapid depletion of proteins in nonplant cells. Nat.Methods 2009 PMID: 19915560

Product Documents for Auxin