BAM 7

Key Product Details

Product Description

BAM 7 is a Bax activator (EC₅₀ = 3.3 μM); binds at the BH3-binding site. Selective for Bax over other antiapoptotic and proapoptotic proteins. Triggers Bax oligomerization in vitro; induces Bax-mediated apoptosis in mouse embryonic fibroblasts.

Product Specifications for BAM 7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for BAM 7

The following data is based on the product molecular weight 405.47.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.66 mL	123.31 mL	246.63 mL
0.5 mM	4.93 mL	24.66 mL	49.33 mL
1 mM	2.47 mL	12.33 mL	24.66 mL
5 mM	0.49 mL	2.47 mL	4.93 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Gavathiotis Direct and selective small-molecule activation of proapoptotic BAX. Nat.Chem.Biol. 2012 PMID: 22634637

Product Documents for BAM 7