BAY 805

Key Product Details

Product Description

BAY 805 is a potent and selective inhibitor of USP21 (IC₅₀ = 6 nM, K_d = 2.2 nM). BAY 805 induces NF-κB activation (EC₅₀= 17 nM in a cell-based reporter assay).

Product Specifications for BAY 805

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for BAY 805

The following data is based on the product molecular weight 507.58.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.97 mL	9.85 mL	19.70 mL
5 mM	0.39 mL	1.97 mL	3.94 mL
10 mM	0.20 mL	0.99 mL	1.97 mL
50 mM	0.04 mL	0.20 mL	0.39 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Göricke Discovery and characterization of BAY-805, a potent and selective inhibitor of ubiquitin-specific protease USP21. J.Med.Chem 2023 PMID: 36802665

Product Documents for BAY 805