BCH
Tocris Bioscience | Catalog # 5027
Product Description
BCH is an inhibitor of L-type amino acid transporter LAT1. Suppresses growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines.
Product Specifications for BCH
Molecular Weight
Formula
Storage
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 15.52 | 100 |
Preparing Stock Solutions for BCH
The following data is based on the product molecular weight 155.20.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.44 mL | 32.22 mL | 64.43 mL |
| 5 mM | 1.29 mL | 6.44 mL | 12.89 mL |
| 10 mM | 0.64 mL | 3.22 mL | 6.44 mL |
| 50 mM | 0.13 mL | 0.64 mL | 1.29 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.
- Lin L-type amino acid transporter-1 overexpression and melp. sensitivity in Barrett's adenocarcinoma. Neoplasia 2004 PMID: 15068672
- Fraga L-type amino acid transporters in two intestinal epithelial cell lines function as exchangers with neutral amino acids. J.Nutr. 2002 PMID: 11925469
- Kim BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells. Biol.Pharm.Bull. 2008 PMID: 18520037
Product Documents for BCH
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for BCH
For research use only
Citations for BCH
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