BD 1047 dihydrobromide

Tocris Bioscience | Catalog # 0956

σ1 selective antagonist
Tocris Bioscience

Key Product Details

Description

σ1 selective antagonist
View all Sigma1 Receptor Antagonists »

Product Description

BD 1047 dihydrobromide is a σ1 receptor antagonist, exhibiting a similar binding profile to that of BD 1063 (Cat. No. 0883) but with higher affinity (approximately 10-fold) at both σ1 and σ2 sites.

Product Specifications for BD 1047 dihydrobromide

Molecular Weight

437.04

Formula

C13H20Cl2N2.2HBr

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine dihydrobromide

CAS Number

138356-21-5

PubChem ID

45073418

InChI Key

WOALTFHGLDVJHK-UHFFFAOYSA-N

SMILES

Br.Br.CN(C)CCN(C)CCC1=CC=C(Cl)C(Cl)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 21.85 50
DMSO 21.85 50

Preparing Stock Solutions for BD 1047 dihydrobromide

The following data is based on the product molecular weight 437.04.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.58 mL 22.88 mL 45.76 mL
2.5 mM 0.92 mL 4.58 mL 9.15 mL
5 mM 0.46 mL 2.29 mL 4.58 mL
25 mM 0.09 mL 0.46 mL 0.92 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 19 publications citing the usage of this product.

Product Documents for BD 1047 dihydrobromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BD 1047 dihydrobromide

For research use only

Citations for BD 1047 dihydrobromide

Customer Reviews for BD 1047 dihydrobromide (1)

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  • Effect of BD 1047 on viability of 661W cells
    Name: Timur Mavlyutov
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: 661W
    Verified Customer | Posted 02/04/2018
    MTT (cell viability assay) of 661W cultured cells. Cells were pretreated with sigma-1 receptor antagonist BD 1047. Results show that 100uM concentration of BD1047 significantly inhibited viability of this cell line.
    BD 1047 dihydrobromide 0956

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