BDNF (human)

Tocris Bioscience | Catalog # 2837

Activates TrkB and p75 receptors
Tocris Bioscience

Key Product Details

Description

Activates TrkB and p75 receptors
View all Trk Receptor Activators »

Product Description

BDNF (human) is a member of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors. BDNF enhances the survival, growth and differentiation of neurons. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease. In an animal model of Huntington's disease, BDNF administration or overexpression rescues the disease phenotype.

Product Specifications for BDNF (human)

Molecular Weight

26984.00

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

218441-99-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

Product Documents for BDNF (human)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BDNF (human)

For research use only

Related Research Areas

Receptor Tyrosine Kinases (RTKs)

Customer Reviews for BDNF (human) (2)

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  • Smooth muscle activation
    Name: Mohammad Alqudah
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Smooth muscle
    Verified Customer | Posted 10/19/2022
    Used to activate primary smooth muscle culture at 1 nM. Good results
  • Increases neurite outgrowth in human neurons
    Name: Karthik Krishnamurthy
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: iPS neurons
    Verified Customer | Posted 11/15/2021
    Used at a concentration of 10 ng/ml. Increases neurite growth in human iPS neurons. The image shows the labeling of MAP-2 in human iPS neurons treated with BDNF for a week.
    BDNF (human) 2837

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