BDY FL Lenalidomide

Tocris Bioscience | Catalog # 7857

Fluorescent cereblon ligand
Tocris Bioscience
Discontinued Product
7857 has been discontinued. View all Fluorescent Ligands products.

Key Product Details

Description

Fluorescent cereblon ligand

Wavelength

Excitation = 506 nm, Emission = 508 nm
View all Fluorescent Ligands »

Product Description

BDY FL Lenalidomide is a fluorescent cereblon ligand. It can be used in time-resolved fluorescence resonance energy-transfer (TR-FRET) cereblon binding assays for PROTAC® Degrader development. This assay is highly sensitive, selective, and stable. Excitation and emission maxima (λ) are 506 and 508 nm, respectively.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Optical Data

BDY FL Lenalidomide Dye Spectra
Emission Color Green
λabs 506 nm
λem 508 nm
Closest Laser line 488 nm
Cell Permeable Yes
Application TR-FRET and FP Assays
Alternative For BDY FL Thalidomide

Spectra Viewer

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Product Specifications for BDY FL Lenalidomide

Molecular Weight

632.52

Formula

C33H39BF2N6O4

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

3-(5,5-Difluoro-7,9-dimethyl-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-N-(6-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)hexyl)propanamide

InChI Key

RCUBMUCPIXRRKQ-UHFFFAOYSA-N

SMILES

O=C(CCC1N2C(C3=C(C2)C(NCCCCCCNC(CCC4=CC=C5N4[B-](F)([N+]6=C(C=C(C6=C5)C)C)F)=O)=CC=C3)=O)NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 6.33 10

Preparing Stock Solutions for BDY FL Lenalidomide

The following data is based on the product molecular weight 632.52.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.81 mL 79.05 mL 158.10 mL
0.5 mM 3.16 mL 15.81 mL 31.62 mL
1 mM 1.58 mL 7.90 mL 15.81 mL
5 mM 0.32 mL 1.58 mL 3.16 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for BDY FL Lenalidomide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BDY FL Lenalidomide

For research use only

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