β-Estradiol

Tocris Bioscience | Catalog # 2824

Endogenous ER agonist
Tocris Bioscience

Key Product Details

Description

Endogenous ER agonist

Alternative Names

17 β-Estradiol
View all Estrogen and Related Receptor Agonists »

Product Description

β

-Estradiol is an endogenous estrogen receptor (ER) agonist (Ki values are 0.12 and 0.13 nM for ERα and ERβ respectively). Also high affinity ligand at membrane estrogen GPR30 receptors.

α-Estradiol also available.

Product Specifications for β-Estradiol

Molecular Weight

272.38

Formula

C18H24O2

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(17β)-Estra-1,3,5(10)-triene-3,17-diol

CAS Number

50-28-2

PubChem ID

5757

InChI Key

VOXZDWNPVJITMN-ZBRFXRBCSA-N

SMILES

[H][C@@]23CCC1=CC(O)=CC=C1[C@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@H]4O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 27.24 100
Ethanol 20.43 75 with gentle warming

Preparing Stock Solutions for β-Estradiol

The following data is based on the product molecular weight 272.38.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.67 mL 18.36 mL 36.71 mL
5 mM 0.73 mL 3.67 mL 7.34 mL
10 mM 0.37 mL 1.84 mL 3.67 mL
50 mM 0.07 mL 0.37 mL 0.73 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 27 publications citing the usage of this product.

Product Documents for β-Estradiol

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for β-Estradiol

For research use only

⚠ WARNING: This product can expose you to chemicals including Estradiol 17B, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

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