BIO 1211

Tocris Bioscience | Catalog # 3910

Selective α4β1 (VLA-4) inhibitor
Tocris Bioscience

Key Product Details

Description

Selective α4β1 (VLA-4) inhibitor
View all Integrin Receptor Inhibitors »

Product Description

BIO 1211 is a selective, high affinity α4β1 (Very Late Antigen 4; VLA-4) inhibitor; displays 200-fold selectivity for the activated form of α4β1 (KD = 70 pM; IC50 = 0.004 μM). Selective for α4β1 over a range of other integrins (IC50 >100 μM for α1β1, α5β1 and α6β1).

Product Specifications for BIO 1211

Molecular Weight

708.80

Formula

C36H48N6O9

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

187735-94-0

PubChem ID

9961766

InChI Key

NVVGCQABIHSJSQ-KFZSMJGVSA-N

SMILES

O=C(CC2=CC=C(NC(NC3=CC=CC=C3C)=O)C=C2)N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)C)C(N1CCC[C@H]1[C@@](O)=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 2mg/ml in water

Calculators

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Product Documents for BIO 1211

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BIO 1211

For research use only

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