Bioymifi

Key Product Details

Product Description

Bioymifi is a DR5 (TRAIL receptor) agonist. Directly binds extracellular domain of DR5 (K_d = 1.2 μM) and induces the formation of DR5 aggregates. Induces apoptosis of glioblastoma cells.

Product Specifications for Bioymifi

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Bioymifi

The following data is based on the product molecular weight 494.32.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.01 mM	202.30 mL	1,011.49 mL	2,022.98 mL
0.05 mM	40.46 mL	202.30 mL	404.60 mL
0.1 mM	20.23 mL	101.15 mL	202.30 mL
0.5 mM	4.05 mL	20.23 mL	40.46 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Wang Small-molecule activation of the TRAIL receptor DR5 in human cancer cells. Nat.Chem.Biol. 2013 PMID: 23292651

Product Documents for Bioymifi