Bombinakinin M

Tocris Bioscience | Catalog # 2371

Potent bradykinin agonist
Tocris Bioscience
Discontinued Product
2371 has been discontinued. View all Bradykinin Receptor Agonists products.

Key Product Details

Description

Potent bradykinin agonist

Alternative Names

Maximakinin

Product Description

Bombinakinin M is a potent bradykinin receptor agonist. Highly selective for mammalian arterial smooth muscle bradykinin receptors, displaying ~ 50-fold greater potency than bradykinin. Elicits dose-dependent contractile effects in smooth muscle of guinea pig ileum (EC50 = 4.0 nM).

Product Specifications for Bombinakinin M

Molecular Weight

2179.55

Formula

C100H159N31O24

Storage

Desiccate at -20°C

CAS Number

509151-65-9

PubChem ID

90473828

InChI Key

ZEEWOWMYALYVCG-UOGIEMGNSA-N

SMILES

[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product.

  • O'Rourke The smooth muscle pharmacology of maximakinin, a receptor-selective, bradykinin-related nonadecapeptide from the venom of the Chinese toad, Bombina maxima. Regul.Peptides
  • Lee Cloning of bradykinin precursor cDNAs from skin of Bombina maxima reveals novel bombinakinin M antagonists and a bradykinin potential peptide. Regul.Peptides
  • Lai A novel bradykinin-related peptide from skin secretions of toad Bombina maxima and its precursor containing six identicals copies of the final product. Biochem.Biophys.Res.Comm.

Product Documents for Bombinakinin M

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Bombinakinin M

For research use only

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