BTS

Key Product Details

Product Description

BTS is a selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC₅₀ ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.

Product Specifications for BTS

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for BTS

The following data is based on the product molecular weight 261.34.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.83 mL	19.13 mL	38.26 mL
5 mM	0.77 mL	3.83 mL	7.65 mL
10 mM	0.38 mL	1.91 mL	3.83 mL
50 mM	0.08 mL	0.38 mL	0.77 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 34 publications citing the usage of this product.

• Ramachandran Skeletal muscle myosin cross-bridge cycling is necessary for myofibrillogenesis. Cell Motil.Cytoskeleton 2003 PMID: 12673599
• Shaw Mechanism of inhibition of skeletal muscle actomyosin by N-benzyl-p-toluenesulfonamide. Biochemistry 2003 PMID: 12755615
• Cheung A small-molecule inhibitor of skeletal muscle myosin II. Nat.Cell.Biol. 2001 PMID: 11744924

Product Documents for BTS