Buprenorphine hydrochloride

Tocris Bioscience | Catalog # 2808

NOP agonist; also displays mixed action δ, κ and μ receptors
Tocris Bioscience
Discontinued Product
2808 has been discontinued. View all Miscellaneous/Non-selective Opioid Compounds products.

Key Product Details

Description

NOP agonist; also displays mixed action δ, κ and μ receptors
View all Miscellaneous/Non-selective Opioid Compounds »

Product Description

Buprenorphine hydrochloride is a ORL1 receptor agonist that also displays mixed antagonist/partial agonist activity at κ, δ and μ-opioid receptors.

Product Specifications for Buprenorphine hydrochloride

Molecular Weight

504.10

Formula

C29H41NO4.HCl

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

[5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol hydrochloride

CAS Number

53152-21-9

PubChem ID

9848989

InChI Key

UAIXRPCCYXNJMQ-HPRIMLMLSA-N

SMILES

OC1=CC=C3C2=C1O[C@@H]([C@@]7(OC)[C@]([C@@](C)(C(C)(C)C)O)([H])C4)[C@]52[C@@]4(CC7)[C@H](N(CC6CC6)CC5)C3.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 12.6 25
Ethanol 25.2 50

Preparing Stock Solutions for Buprenorphine hydrochloride

The following data is based on the product molecular weight 504.10.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.97 mL 19.84 mL 39.67 mL
2.5 mM 0.79 mL 3.97 mL 7.93 mL
5 mM 0.40 mL 1.98 mL 3.97 mL
25 mM 0.08 mL 0.40 mL 0.79 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 42 publications citing the usage of this product.

Product Documents for Buprenorphine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Buprenorphine hydrochloride

For research use only

Citations for Buprenorphine hydrochloride

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