CaCCinh-A01

Tocris Bioscience | Catalog # 4877

Calcium-activated chloride channel (CaCC) inhibitor
Tocris Bioscience

Key Product Details

Description

Calcium-activated chloride channel (CaCC) inhibitor
View all Calcium-activated Chloride Channel Blockers »

Product Description

CaCCinh-A01 is a calcium-activated chloride channel (CaCC) inhibitor (IC50 ~ 10 μM). Inhibits CaCC currents in human bronchial and intestinal cells. Also inhibits TMEM16A channels (IC50 = 2.1 μM, in TMEM16A-expressing FRT cells).

Product Specifications for CaCCinh-A01

Molecular Weight

347.43

Formula

C18H21NO4S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid

CAS Number

407587-33-1

PubChem ID

2898877

InChI Key

ACLUEOBQFRYTQS-UHFFFAOYSA-N

SMILES

CC(C)(C)C1CCC2=C(SC(NC(C3=CC=CO3)=O)=C2C(O)=O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 34.74 100
Ethanol 3.47 10 with gentle warming

Preparing Stock Solutions for CaCCinh-A01

The following data is based on the product molecular weight 347.43.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.88 mL 14.39 mL 28.78 mL
5 mM 0.58 mL 2.88 mL 5.76 mL
10 mM 0.29 mL 1.44 mL 2.88 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 35 publications citing the usage of this product.

Product Documents for CaCCinh-A01

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CaCCinh-A01

For research use only

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