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Caspase-6 Activity Assay Kit (Colorimetric)
Novus Biologicals | Catalog # NBP3-50232
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Key Product Details
Sample Type & Volume Required Per Well
Cell and tissue samples
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Product Specifications
Kit Type
Activity Assay Kit (Colorimetric)
Species
Non-species specific
Description
Caspase 6, also known as Mch-2, was originally discovered in human Jurkat cells. The precursor of caspase 6 can be cleaved by granzyme B to form an activated caspase 6 dimer, which is found to induce apoptosis. Caspase 6 can cleave PARP and keratin-18, and also cleave Lamin A, a key component protein on the nuclear envelope. Only caspase 6 can cleave Lamin A in the caspase family. This caspase 6 activity assay kit is based on caspase 6 that can catalyze the substrate Ac-VEID-pNA to generate yellow pNA (p-Nitroaniline). The pNA has a strong absorption near 405 nm, The activity of caspase 6 can be calculated by determining the absorbance at 405 nm.
Scientific Data Images for Caspase-6 Activity Assay Kit (Colorimetric)
Application: Caspase-6 Activity Assay Kit (Colorimetric) [NBP3-50232]
Standard Curve of Caspase-6 Activity Assay Kit (Colorimetric) [NBP3-50232]Preparation and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C.
Background: Caspase-6
Alternate Names
CASP6, Caspase6, Mch2
Gene Symbol
CASP6
Additional Caspase-6 Products
Product Documents for Caspase-6 Activity Assay Kit (Colorimetric)
Certificate of Analysis
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Product Specific Notices for Caspase-6 Activity Assay Kit (Colorimetric)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.
Related Research Areas
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