CCT 369260

Key Product Details

Product Description

CCT 369260 acts as a potent BCL6 molecular glue Degrader (IC₅₀ = 54 nM). It reduces BCL6 levels in a lymphoma xenograft mouse model. CCT 369260 is orally bioavailable.

Product Specifications for CCT 369260

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CCT 369260

The following data is based on the product molecular weight 509.00.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	3.93 mL	19.65 mL	39.29 mL
2.5 mM	0.79 mL	3.93 mL	7.86 mL
5 mM	0.39 mL	1.96 mL	3.93 mL
25 mM	0.08 mL	0.39 mL	0.79 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Bellenie Achieving in vivo target depletion through the discovery and optimization of Benzimidazolone BCL6 degraders. J.Med.Chem. 2020 PMID: 32275432

Product Documents for CCT 369260