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CKD 602

Catalog #: 5125 Datasheet / COA / SDS

Discontinued Product

5125 has been discontinued.
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CKD 602 | DNA Topoisomerase Inhibitors
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Description: Topoisomerase I inhibitor
Alternative Names: Belotecan,Camtobell®

Chemical Name: (4S)-4-Ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione phosphate

Purity: ≥98%

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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

CKD 602 is a topoisomerase I inhibitor. Forms stable DNA-topoisomerase complexes during DNA replication and induces cell cycle arrest in the G2/M phase. Inhibits growth of a range of cancer cell lines in vitro, as well as of ovarian and leukemia tumors in vivo.

Technical Data

M.Wt:
531.49
Formula:
C25H27N3O4.H3PO4
Solubility:
Soluble to 20 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
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Reconstitution Calculator

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