Clofibrate
Tocris Bioscience | Catalog # 0824
Product Description
Clofibrate is a PPAR agonist (EC50 values are 50, 500 and > 100 μM at PPARα, PPARγ and PPARδ respectively). Antihyperlipoproteinemic.
Product Specifications for Clofibrate
Molecular Weight
Formula
Storage
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 24.27 | 100 |
Preparing Stock Solutions for Clofibrate
The following data is based on the product molecular weight 242.7017.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.12 mL | 20.60 mL | 41.20 mL |
| 5 mM | 0.82 mL | 4.12 mL | 8.24 mL |
| 10 mM | 0.41 mL | 2.06 mL | 4.12 mL |
| 50 mM | 0.08 mL | 0.41 mL | 0.82 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.
- Shepherd Mechanism of action of fibrates. Postgrad.Med.J. 1993 PMID: 8497455
- Willson The PPARs: from orphan receptors to drug discovery. J.Med.Chem. 2000 PMID: 10691680
- Bishop-Bailey Peroxisome proliferator-activated receptors in the cardiovascular system. Br.J.Pharmacol. 2000 PMID: 10696077
Product Documents for Clofibrate
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Clofibrate
For research use only
⚠ WARNING: This product can expose you to chemicals including Clofibrate, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.govRelated Research Areas
Citations for Clofibrate
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