Coenzyme Q10
Tocris Bioscience | Catalog # 3003
Product Description
Coenzyme Q10 is a component of the mitochondrial transporter chain that behaves as a powerful antioxidant. Coenzyme Q10 displays neuroprotective activity. In an animal model of Huntington's disease, Coenzyme Q10 extends survival and delays disease; this effect is more pronounced when combined with Remacemide hydrochloride (Cat. No. 1622). Ferroptosis inhibitor.
Product Specifications for Coenzyme Q10
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| chloroform | 43.17 | 50 | |
| Ethanol | 4.32 | 5 with gentle warming |
Preparing Stock Solutions for Coenzyme Q10
The following data is based on the product molecular weight 863.34.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 2.32 mL | 11.58 mL | 23.17 mL |
| 2.5 mM | 0.46 mL | 2.32 mL | 4.63 mL |
| 5 mM | 0.23 mL | 1.16 mL | 2.32 mL |
| 25 mM | 0.05 mL | 0.23 mL | 0.46 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 20 publications citing the usage of this product.
- Ferrante Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease. J.Neurosci. 2002 PMID: 11880489
- Young Coenzyme Q10: a review of its promise as a neuroprotectant. CNS Spectr. 2007 PMID: 17192765
- Yang and Stockwell Ferroptosis: Death by lipid peroxidation. Trends Cell Biol. 2016 PMID: 26653790
- Shults Coenzyme Q10 in neurodegenerative diseases. Curr.Med.Chem. 2003 PMID: 12871093
Product Documents for Coenzyme Q10
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Coenzyme Q10
For research use only
Citations for Coenzyme Q10
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