Congo Red

Tocris Bioscience | Catalog # 5167

Amyloid fibril binding dye; also a VGlut inhibitor
Tocris Bioscience
Discontinued Product
5167 has been discontinued. View all Fluorescent Amyloid B Probes products.

Key Product Details

Description

Amyloid fibril binding dye; also a VGlut inhibitor
View all Fluorescent Amyloid B Probes »

Product Description

Congo Red is a VGlut inhibitor; decreases synaptic transmission in the dentate gyrus. Also an amyloid fibril-binding dye; inhibits Fib-beta A neurotoxicity by inhibiting fibril formation or by binding to preformed fibrils. Also inhibits the pancreatic islet cell toxicity of diabetes-associated amylin. Excitation wavelength is 497 nm.

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Product Specifications for Congo Red

Molecular Weight

696.66

Formula

C32H22N6Na2O6S2

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

3,3'-[(1,1'-Biphenyl)-4,4'-diyl-bis(2,1-diazenediyl)]bis(4-amino-1-naphthalenesulfonic acid) disodium salt

CAS Number

573-58-0

PubChem ID

11313

InChI Key

IQFVPQOLBLOTPF-UHFFFAOYSA-L

SMILES

NC2=C(/N=N/C3=CC=C(C4=CC=C(/N=N/C5=C(N)C(C=CC=C6)=C6C(S(=O)(O[Na])=O)=C5)C=C4)C=C3)C=C(S(=O)(O[Na])=O)C1=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 6.97 10
DMSO 6.97 10

Preparing Stock Solutions for Congo Red

The following data is based on the product molecular weight 696.66.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.35 mL 71.77 mL 143.54 mL
0.5 mM 2.87 mL 14.35 mL 28.71 mL
1 mM 1.44 mL 7.18 mL 14.35 mL
5 mM 0.29 mL 1.44 mL 2.87 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for Congo Red

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Congo Red

For research use only

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