CPCCOEt

Tocris Bioscience | Catalog # 1028

Selective non-competitive mGlu1 antagonist
Tocris Bioscience

Key Product Details

Description

Selective non-competitive mGlu1 antagonist
View all Group I mGluR Antagonists »

Product Description

CPCCOEt is a hmGlu1 subtype-selective non-competitive antagonist (IC50 = 6.5 μM). Has no agonist or antagonist activity at hmGlu2, 4a, 5a, 7b, 8a or ionotropic receptors at concentrations of up to 100 μM.

Licensing Information

Sold for research purposes under license from Suntory Ltd.

Product Specifications for CPCCOEt

Molecular Weight

247.25

Formula

C13H13NO4

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylate ethyl ester

CAS Number

179067-99-3

PubChem ID

6278000

InChI Key

FXCTZFMSAHZQTR-KAMYIIQDSA-N

SMILES

O=C(OCC)C3(C2C3)OC1=CC=CC=C1/C2=N/O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 24.73 100
Ethanol 1.24 5

Preparing Stock Solutions for CPCCOEt

The following data is based on the product molecular weight 247.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.04 mL 20.22 mL 40.44 mL
5 mM 0.81 mL 4.04 mL 8.09 mL
10 mM 0.40 mL 2.02 mL 4.04 mL
50 mM 0.08 mL 0.40 mL 0.81 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 188 publications citing the usage of this product.

Product Documents for CPCCOEt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CPCCOEt

For research use only

Customer Reviews for CPCCOEt (1)

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  • Succesfull block of mGluRs
    Name: Anonymous
    Assay Type: In Vitro
    Verified Customer | Posted 11/02/2017
    We use bath application of CPCCOEt and MPEP to block mGluRs.

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