CST 530

Key Product Details

Product Description

CST 530 is a monovalent IAP antagonist. Induces cIAP1 and cIAP2 autodegradation in MM.1S cells (degrades cIAP1 at 0.1μM and cIAP2 at 1μM, after 16h). CST 530 reduces cell viability in a variety of cancer cell lines including SUDHL6, MOLM13 and HEL (IC₅₀ values are 170 nM, 420 nM and 450 nM respectively).

Product Specifications for CST 530

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CST 530

The following data is based on the product molecular weight 560.74.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.78 mL	8.92 mL	17.83 mL
5 mM	0.36 mL	1.78 mL	3.57 mL
10 mM	0.18 mL	0.89 mL	1.78 mL
50 mM	0.04 mL	0.18 mL	0.36 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Ng Heterobifunctional ligase recruiters enable pan-degradation of inhibitor of apoptosis proteins. J.Med.Chem. 2023 PMID: 36996313

Product Documents for CST 530