CXCL2/GRO beta/MIP-2/CINC-3 Antibody - Azide and BSA Free

Novus Biologicals | Catalog # NBP3-03233

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Rat

Cited:

Mouse

Applications

Validated:

Western Blot

Cited:

Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free
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Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human CXCL2/GRO beta/MIP-2/CINC-3 (NP_002080.1). MARATLSAAPSNPRLLRVALLLLLLVAASRRAAGAPLATELRCQCLQTLQGIHLKNIQSVKVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNGKSN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

11 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit CXCL2/GRO beta/MIP-2/CINC-3 Antibody - Azide and BSA Free (NBP3-03233) is a polyclonal antibody validated for use in IHC and WB. Anti-CXCL2/GRO beta/MIP-2/CINC-3 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CXCL2/GRO beta/MIP-2/CINC-3 Antibody - Azide and BSA Free

Western Blot: CXCL2/GRO beta/MIP-2/CINC-3 AntibodyAzide and BSA Free [NBP3-03233]

Western Blot: CXCL2/GRO beta/MIP-2/CINC-3 AntibodyAzide and BSA Free [NBP3-03233]

Western Blot: CXCL2/GRO beta/MIP-2/CINC-3 Antibody [NBP3-03233] - Analysis of extracts of rat lung, using CxCL2/GRO beta/MIP-2/CINC-3 antibody at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Applications for CXCL2/GRO beta/MIP-2/CINC-3 Antibody - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

Azide and BSA Free

Preservative

0.01% Thimerosal

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CXCL2/GRO beta/MIP-2/CINC-3

CXCL2/GRO beta, also called MIP-2 in mouse and CINC-3 in rat, is a member of the CXC chemokine family. Human CXCL2/GRO beta is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 70% and 71% aa sequence identity with the human protein, respectively. N-terminal aa 1-4 of CXCL2/GRO beta can be post-translationally cleaved which confers enhanced hematopoietic bioactivity. CXCL2/GRO beta is produced by a variety of cell types including monocytes and macrophages at sites of inflammation and is chemotactic for granulocytes, including neutrophils.

Alternate Names

CINC-3, CINC3, GRO beta, MGSA-beta, MIP-2

Gene Symbol

CXCL2

Additional CXCL2/GRO beta/MIP-2/CINC-3 Products

Product Documents for CXCL2/GRO beta/MIP-2/CINC-3 Antibody - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CXCL2/GRO beta/MIP-2/CINC-3 Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Citations for CXCL2/GRO beta/MIP-2/CINC-3 Antibody - Azide and BSA Free

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FAQs for CXCL2/GRO beta/MIP-2/CINC-3 Antibody - Azide and BSA Free

Showing  1 - 11 FAQ Showing All
    • A: Mouse and rat do not have a gene which encodes CXCL8/IL-8. In mouse, the functional homologs to human CXCL8/IL-8 are CXCL1/KC and CXCL2/MIP-2. In rat, the functional homolog to CXCL8/human IL-8 is CXCL3/CINC-2.
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