CYM 50260

Key Product Details

Product Description

CYM 50260 is a potent sphingosine-1-phosphate receptor 4 (S1P₄) agonist (EC₅₀ = 45 nM). Displays no activity at other S1P receptor subtypes (S1P_1-3 and S1P₅) at concentrations up to 25 μM.

Product Specifications for CYM 50260

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CYM 50260

The following data is based on the product molecular weight 350.60.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.85 mL	14.26 mL	28.52 mL
5 mM	0.57 mL	2.85 mL	5.70 mL
10 mM	0.29 mL	1.43 mL	2.85 mL
50 mM	0.06 mL	0.29 mL	0.57 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

• Guerrero Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P₄-R) agonists. Bioorg.Med.Chem.Lett. 2011 PMID: 22119461

Product Documents for CYM 50260