Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a type I transmembrane protein belonging to the SIRP/SHPS (CD172) family within the Ig superfamily. SIRP gamma is expressed on T cells, CD56bright NK cells and activated NK cells, but not myeloid cells. Like SIRP alpha, it binds CD47, but unlike SIRP alpha, it does not contain an obvious signaling mechanism. T cell SIRP gamma may play a role as an accessory protein interacting with CD47-expressing antigen presenting cells, and appears to promote antigen-specific T cell proliferation and costimulate T cell activation.
Cyno Monkey SIRP gamma/CD172g (XP_005568591) VersaClone cDNA
R&D Systems | Catalog # RDC2660
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Background: SIRP gamma/CD172g
Long Name
Signal-regulatory Protein gamma
Alternate Names
CD172g, SIRP beta 2, SIRPG
Gene Symbol
SIRPG
UniProt
Additional SIRP gamma/CD172g Products
Product Documents for Cyno Monkey SIRP gamma/CD172g (XP_005568591) VersaClone cDNA
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Product Specific Notices for Cyno Monkey SIRP gamma/CD172g (XP_005568591) VersaClone cDNA
For research use only
Related Research Areas
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