Cytochalasin D

Tocris Bioscience | Catalog # 1233

Disrupts actin filament function
Tocris Bioscience

Key Product Details

Description

Disrupts actin filament function

Alternative Names

Zygosporin A
View all Actin-related Products »

Product Description

Cytochalasin D is a potent disruptor of actin filament function. Alters tight junction permeability. Unlike cytochalasin B (Cat. No. 5474), does not inhibit monosaccharide transport across the plasma membrane.

Product Specifications for Cytochalasin D

Molecular Weight

507.63

Formula

C30H37NO6

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione

CAS Number

22144-77-0

PubChem ID

98137101

InChI Key

SDZRWUKZFQQKKV-HYKYWQBKSA-N

SMILES

C=C([C@H]4C)[C@@H](O)[C@]([C@@]1([C@H](OC(C)=O)/C=C/[C@@](O)3C)[C@]4([H])[C@@H](CC2=CC=CC=C2)N[C@]1=O)([H])/C=C/C[C@H](C)C3=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 25 50
Ethanol 5 10 with gentle warming

Preparing Stock Solutions for Cytochalasin D

The following data is based on the product molecular weight 507.63.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.94 mL 19.70 mL 39.40 mL
2.5 mM 0.79 mL 3.94 mL 7.88 mL
5 mM 0.39 mL 1.97 mL 3.94 mL
25 mM 0.08 mL 0.39 mL 0.79 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 147 publications citing the usage of this product.

Product Documents for Cytochalasin D

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Cytochalasin D

For research use only

Customer Reviews for Cytochalasin D (1)

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  • Cytochalasin D
    Name: Clara Lubeseder-Martellato
    Species: Mouse
    Assay Type: Ex Vivo
    Verified Customer | Posted 11/12/2021
    It was used as an inhibitor in cell culture and in 3-dimensional cultures. Concentrations tested from 1 uM to 10 uM for 48n hours for 2D cultures and 4 days for 3D cultures
    Cytochalasin D 1233

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