D-CPP-ene

Key Product Details

Product Description

D-CPP-ene is a potent and competitive NMDA antagonist (K_i = 40 nM). Centrally active following systemic administration.

Product Specifications for D-CPP-ene

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for D-CPP-ene

The following data is based on the product molecular weight 250.19.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.00 mL	19.98 mL	39.97 mL
5 mM	0.80 mL	4.00 mL	7.99 mL
10 mM	0.40 mL	2.00 mL	4.00 mL
50 mM	0.08 mL	0.40 mL	0.80 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 14 publications citing the usage of this product.

• Potschka Effects of the NMDA receptor antagonist D-CPPene on extracellular levels of DA and DA and serotonin metabolites in striatum of kindled and non-kindled rats. Eur.J.Pharmacol. 1999 PMID: 10422758
• Aebischer Synthesis and NMDA antagonistic properties of the enantiomers of 4-(3-phosphonopropyl)piperazine-2-carboxylic acid (CPP) and of the unsaturated analogue (E)-4-(3-phosphono-2-enyl)piperazine-2-carboxylic acid (CPP-ene). Helv.Chim.Acta
• Lowe D-CPP-ene (SDZ EAA 494), a potent and competitive N-MthD.-aspartate (NMDA) antagonist: effect on spontaneous activity and NMDA-induced depolarizations in the rat neocortical slice preparation, compared with other CPP derivatives and MK-801. Neurosci.Lett. 1990 PMID: 2166255

Product Documents for D-CPP-ene