DADPS Biotin Azide
Tocris Bioscience | Catalog # 7966
Key Product Details
Description
Product Description
DADPS Biotin Azide is an acid cleavable biotin capture reagent, with an azide group as a click handle for conjugation. The biotin portion strongly binds to avidin or streptavidin to allow isolation of specific, tagged proteins or cells from a complex biological mixture. The DADPS component is a cleavable linker, which can be cleaved under very mild acidic treatment (such as 10% formic acid), unlike traditional biotin probes that require harsh conditions (which can damage samples) to break the streptavidin bond.
Product Specifications for DADPS Biotin Azide
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 88.62 | 100 |
Preparing Stock Solutions for DADPS Biotin Azide
The following data is based on the product molecular weight 886.19.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.13 mL | 5.64 mL | 11.28 mL |
| 5 mM | 0.23 mL | 1.13 mL | 2.26 mL |
| 10 mM | 0.11 mL | 0.56 mL | 1.13 mL |
| 50 mM | 0.02 mL | 0.11 mL | 0.23 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Li Benchmarking cleavable biotin tags for peptide-centric chemoproteomics. J.Proteome Res. 2022 PMID: 35467356
- Lai Quantitative site-specific chemoproteomic profiling of protein lipoylation. JACS 2022 PMID: 35648456
- Ruan Proteome-wide deconvolution of drug targets and binding sites by lysine reactivity profiling. Anal.Chem. 2022 PMID: 35147412
- McConnell Maleimide-based chemical proteomics for quantitative analysis of cysteine reactivity. J.Am.Soc.Mass Spectrom. 2020 PMID: 32573231
- Rabalski Evaluation of chemically-cleavable linkers for quantitative mapping of small molecule-cysteinome reactivity. ACS Chem.Biol. 2019 PMID: 31430117
- Li Characterization of the artemisinin binding site for translationally controlled tumor protein (TCTP) by bioorthogonal click chemistry. Bioconj.Chem. 2016 PMID: 27998071
Product Documents for DADPS Biotin Azide
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for DADPS Biotin Azide
For research use only
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