DL-Dithiothreitol

Key Product Details

Product Description

DL-Dithiothreitol is a reagent for maintaining SH groups in the reduced state.

Product Specifications for DL-Dithiothreitol

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for DL-Dithiothreitol

The following data is based on the product molecular weight 154.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

11 10 9 8 7 6 5 4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	6.48 mL	32.41 mL	64.83 mL
5 mM	1.30 mL	6.48 mL	12.97 mL
10 mM	0.65 mL	3.24 mL	6.48 mL
50 mM	0.13 mL	0.65 mL	1.30 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Cleland Dithiothreitol, a new protective group for SH groups. Biochemistry 1964 PMID: 14192894
• Sears Relative susceptibilities of the interchain disulfides of an immunoglobulin G molecule to reduction by dithiothreitol. Biochemistry 1977 PMID: 403938
• Jabusch The effect of thiodiglycol and dithiothreitol on the alkaline hydrolysis products of certain amino acid phenylthiohydantoins. Anal.Biochem. 1978 PMID: 9762140
• Rüegg and Rudinger Reductive cleavage of cystine disulfides with tributylphosphine. Methods Enzymol. 1977 PMID: 927167

Product Documents for DL-Dithiothreitol