DMHBO+

Tocris Bioscience | Catalog # 7764

Fluorescent upon binding to Chili aptamer; for imaging RNA in cells
Tocris Bioscience
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Key Product Details

Description

Fluorescent upon binding to Chili aptamer; for imaging RNA in cells

Wavelength

Excitation = 456 nm, Emission = 592 nm

Product Description

DMHBO+ is a cationic fluorophore. Its fluorescence is activated by binding to chili aptamer (Kd = 12 nM). Chili-DMHBO+ complex mimics red fluorescent proteins, suitable for imaging RNA in cells. It is an ideal FRET donor to the rhodamine dye Atto 590 and has applications in FRET-based analytical RNA systems. Excitation/emission maxima (λ) = 456/592 nm; quantum yield = 0.1; stokes shift = 136 nm.

Optical Data

λabs 456 nm
λem 592 nm
Quantum Yield (φ) 0.1
Application Time-resolved fluorescence energy transfer (TR-FRET)

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Product Specifications for DMHBO+

Molecular Weight

552.37

Formula

C22H25IN4O5

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

4-(4-((Z)-4-Hydroxy-3,5-dimethoxybenzylidene)-2-((hydroxyimino)methyl)-5-oxo-4,5-dihydro-1H-imidazol-1-yl)-N,N,N-trimethylbenzenaminium iodide

CAS Number

2322286-81-5

InChI Key

KRIJKRIPLDZXHI-UHFFFAOYSA-N

SMILES

O/N=C/C(N(C1=CC=C(C=C1)[N+](C)(C)C)C/2=O)=NC2=C/C3=CC(OC)=C(C(OC)=C3)O.[I-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 27.62 50

Preparing Stock Solutions for DMHBO+

The following data is based on the product molecular weight 552.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.62 mL 18.10 mL 36.21 mL
2.5 mM 0.72 mL 3.62 mL 7.24 mL
5 mM 0.36 mL 1.81 mL 3.62 mL
25 mM 0.07 mL 0.36 mL 0.72 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for DMHBO+

Certificate of Analysis

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Product Specific Notices for DMHBO+

For research use only

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